The LSU Tigers are 3-0 and ranked as the No. 3 team in the country in the Week 4 AP Top 25 Poll. Brian Kelly's squad is set for an in-state matchup against FCS Southeastern Louisiana in Week 4 before heading to Oxford for a big tilt at No. 13 Ole Miss.
The Southeastern Louisiana Lions enter Tiger Stadium with a 2-1 record and are coming off a big 56-3 win over Mississippi Valley State last week. The Tigers and Lions have a common opponent this season, as both teams have played the Louisiana Tech Bulldogs. SLU fell to Louisiana Tech 24-0 in Week 1, and LSU defeated Tech 23-7 in Week 2.
LSU vs Southeastern Louisiana betting odds
Betting odds for Saturday's matchup weren't available on most US sportsbooks when lines for Week 4 games were originally released last Sunday. That's not entirely uncommon when a top FBS team is playing a team from the FCS level. Sometimes betting odds for these types of game are never even posted. But now that kick-off is less than 48 hours away, LSU vs Southeastern Louisiana betting odds are available on FanDuel Sportsbook.
It's not surprising to see oddsmakers favoring LSU by a wide margin. As of 8:00 a.m. ET on Friday, September 19, LSU is favored by 39.5 points. The total, or over/under, is listed at 51.5. Moneyline odds are not available on FanDuel.
So far this season, LSU is 3-0 overall and 2-1 against the spread. The Tigers covered the spread against Clemson and Florida, but failed to cover the 36.5-point spread against Louisiana Tech in Week 2. The under is 3-0 for LSU so far this season.
LSU and Southeastern Louisiana have met just twice in their respective histories, with LSU winning 48-7 in 1949 and 31-0 in 2018. Kick-off for Saturday night is slated for 6:45 p.m. CT.