LSU picked up an impressive 17-10 win on the road at No. 4 Clemson to open the 2025 season. It wasn't always pretty, but LSU found a way to earn a gutsy win that has the Tigers with a 1-0 start for the first time since 2019. The win has college football fans around the country talking, as LSU's new-look defense dominated Cade Klubnik and company from start to finish. LSU is riding high after the momentous victory, and Brian Kelly's squad is looking to keep things rolling in Week 2.
LSU vs Louisiana Tech early betting odds
LSU welcomes Louisiana Tech to Tiger Stadium on Saturday, Sept. 6 in Week 2. Not surprisingly, professional oddsmakers are favoring LSU by a wide margin. As of 8:00 p.m. ET on Sunday, August 31, DraftKings has LSU favored by a whopping 38.5 points. The total, or over/under, is listed at 52.5.
So far this season, LSU is 1-0 overall and 1-0 against the spread. The Tigers were 4.5-point underdogs at Clemson, and won the game outright. The under is 1-0 for LSU so far this season.
Louisiana Tech is 1-0 overall and 1-0 against the spread. The Bulldogs defeated Southeastern Louisiana in Week 1 by a score of 24-0. Sonny Cumbie's squad was favored by 14.5 points, so their 24-point victory was enough to cover the spread. The under is 1-0 for Louisiana Tech as well.
The Tigers and Bulldogs have met 20 times before. LSU owns a strong 19-1 advantage in the series, with Louisiana Tech's lone win coming all the way back in 1905 by a score of 6-0 in Ruston. LSU has won 16 consecutive matchups since then, with the most recent victory coming in 2018 at Tiger Stadium by a score of 38-21. Kick-off for the in-state matchup is slated for 7:30 p.m. ET on Saturday night.