The LSU Tigers head to Norman to face the Oklahoma Sooners in the final regular season game of the 2025 season. The Tigers entered the season with hopes of competing for a National Championship, but now are just looking to salvage and eight-win season.
Lane Kiffin leaves fans guessing in Egg Bowl postgame interview
Interim head coach Frank Wilson is 2-1 at the helm of the LSU program, and looking to lead the Tigers to a three-game winning streak to close the season. It's a tough task, as the Sooners are ranked as the No. 8 team in the country and own one of the best defenses in college football. As kick-off draws nearer, here is a look at the updated LSU vs Oklahoma betting odds as well as a score prediction.
LSU vs Oklahoma betting odds
As of 11:00 a.m. CT on Saturday, November 29, the Tigers find themselves as 10.5-point underdogs against the Sooners on DraftKings Sportsbook. When it comes to the moneyline, LSU has underdog odds of +360 while Oklahoma has odds of -470. Oddsmakers are expecting a low-scoring games, as the total, or over/under, is listed at 35.5, which is the lowest total of any LSU game this season.
Spread
- LSU +10.5 (-108)
- Oklahoma -10.5 (-112)
Moneyline
- LSU +360
- Oklahoma -470
Total
- 35.5 (Over -115, Under -105)
LSU vs Oklahoma prediction
Obviously, the LSU Football program will be tuned in to the off-the-field happenings related to Lane Kiffin's announcement. It's possible that has an impact on LSU's focus level heading into Norman. But on the field, the Tigers have their hands full and could be out-matched by Brent Venables' squad. LSU has managed to score just 19.3 points per game against FBS opponents this season, and things won't get any easier going up against one of the best defenses in the country. Oklahoma ranks sixth in the country in scoring defense allowing 14.0 points per game to their opponents.
The offensive line is a major area of concern for LSU, and Oklahoma leads the country in sacks on the season. The mobility of Michael Van Buren may help a little bit, but avoiding negative plays will be a huge point of emphasis for the LSU offense. The downfield passing game hasn't materialized on a consistent basis all season long, and the running game has been an area of concern as well.
John Mateer has gotten healthier and healthier since his finger surgery nearly two months ago, and LSU has struggled against mobile quarterbacks all season long. It seems that LSU could be severely out-matched on both sides of the ball, which means it could take a near perfect game from the Tigers and several errors from the Sooners for LSU to pull off the upset in this one.
Score prediction: Oklahoma wins 27-13