After back-to-back wins over Arkansas and Western Kentucky, LSU is looking to cap the 2025 regular season with a three-game win streak in Week 14 against the Oklahoma Sooners. It will be a tough task, as Brent Venables' squad is ranked as the No. 8 team in the country and own a 9-2 record on the season.
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As interim head coach Frank Wilson prepares his team to battle the Sooners, much attention is being paid to the Lane Kiffin sweepstakes happening off the field. Kiffin is expected to make a public announcement regaring his future on Saturday - the same day that LSU takes on Oklahoma. Needless to say, it's shaping up to be a pivotal weekend for the LSU Football program.
LSU vs Oklahoma early betting odds
Professional oddsmakers are favoring the Sooners by double digits in this one. As of 6:30 p.m.CT on Sunday, November 23, Oklahoma is favored by 10.5 points on FanDuel Sportsbook. When it comes to the moneyline, LSU has underdog odds of +315 while Oklahoma has odds of -410. The total, or over/under, is listed at 38.5.
LSU vs Oklahoma spread
- LSU +10.5 (-122)
- Oklahoma -10.5 (+100)
LSU vs Oklahoma moneyline
- LSU +315
- Oklahoma -410
LSU vs Oklahoma total
- 38.5 (Over -110, Under -110)
So far this season, LSU is 7-4 straight up and and just 3-8 against the spread. In their last game, the Tigers were favored by 22.5 points over WKU but won by just three. LSU has not covered the spread since defeating South Carolina 20-10 back on October 11. Low-scoring games have been a theme for the Tigers in 2025, as the Under has cashed in eight of LSU's 11 games.
On the other side, Oklahoma is 9-2 straight up and 6-4-1 against the spread. Oklahoma covered the 4.5-point spread this past weekend with a 17-6 victory over Missouri. The Sooners have now covered the spread in three straight games and in four of their last five games. Oklahoma has also seen plenty of low-scoring games this season, as the Under is 8-3 in their 11 games.
LSU won last year's meeting by a score of 37-17 in Baton Rouge in the first-ever SEC meeting between the Tigers and Sooners. Kick-off for Saturday's matchup in Norman is set for 2:30 p.m. CT from Memorial Stadium. The game will be broadcast on ABC.