The wait is almost over. The college football season is officially underway, and after a small five-game slate in Week 0, the floodgates are set to open on the 2025 college football season this weekend. One of the biggest games of the weekend sees No. 9 LSU travel to No. 4 Clemson for an enormous matchup between two National Championship hopefuls. Furthermore, both quarterbacks in this matchup, Garrett Nussmeier and Cade Klubnik, are firmly in the Heisman Trophy conversation.
It's a massive game for Brian Kelly and LSU, as the Tigers are looking for their first 1-0 start since 2019. It's Clemson's first season opener at home since 2019, so the crowd at Memorial Stadium is sure to be jumping early and often. We could have the makings of an instant classic on our hands. Here's everything you need to know ahead of this highly-anticipated matchup.
How to watch No. 9 LSU at No. 3 Clemson in Week 1
- Date: Saturday, August 30
- Time: 7:30 p.m. ET
- Venue: Memorial Stadium (Clemson, SC)
- How to Watch (TV): ABC
- Streaming: YouTube TV, fuboTV, Hulu + Live TV, DirecTV Stream
- LSU record: 0-0
- Clemson record: 0-0
What are the current odds for LSU vs Clemson?
The spread for this top-10 matchup has hovered back-and-forth between 3.5-4 points in Clemson's favor. As of 8:00 p.m. ET on Tuesday, Aug. 26, here are the betting odds for LSU vs Clemson on BetMGM Sportsbook:
Moneyline
- LSU +150
- Clemson -185
Spread
- LSU +4 (-110)
- Clemson -4 (-110)
Total
- 57.5 (Over -110/Under -110)
Injury updates for LSU vs Clemson
Both teams are fairly healthy entering this contest, and both squads should have deep rotations available on both sides of the ball. With that being said, here are some situations worth monitoring:
LSU injury report
- RB JT Lindsey: OUT (Suspension)
- QB Michael Van Buren Jr.: Questionable (Undisclosed)
- WR Nic Anderson: Questionable (Concussion)
Clemson injury report
- TE Ian Schieffelin: OUT (Suspension)
- RB Jay Haynes: OUT (Knee)
- RB Jarvis Green: OUT (Foot)
- WR Juju Preston: Questionable (Hamstring)
- TE Olsen Patt-Henry: Questionable (Mouth)
Who are the announcers for LSU vs Clemson?
The LSU vs Clemson game will be broadcast on ABC. Thankfully, the ABC broadcast is not impacted by the ongoing carriage dispute between FOX Sports and YouTube TV. LSU fans will be familair with the broadcast team, as ESPN's top college football broadcast team will be on the call. Play-by-play man Chris Fowler, color analyst Kirk Herbstreit, and sideline reporters Holly Rowe and Molly McGrath will be on the call from Memorial Stadium.
What is the series history between LSU and Clemson?
LSU all-time head-to-head record vs Clemson: 3-1
Last meeting: LSU defeated Clemson in the College Football Playoff Championship Game by a score of 42-25 on Jan. 13, 2020.
What is the weather forecast for LSU vs Clemson?
The weather should be great in Clemson, SC on Saturday evening. The projected kick-off temperature sits at 76 degrees, and the temperature should stay in the mid-70s throughout the game. Inclement weather is not projected to be an issue.
Wow, this looks like great @LSUfootball season opening weather! @ClemsonFB pic.twitter.com/OkHNvZlFGe
— Jacques Doucet (@JacquesDoucet) August 25, 2025